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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Osthole
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
484-12-8
- 规格:
20mg
蛇床子素
分析标准品,HPLC≥98%
Osthole
CAS号:484-12-8
分子式:C15H16O3
分子量:244.29
MDL:MFCD00076049
别名:7-甲氧基-8-异戊烯基香豆素,喔斯脑,欧芹酚甲*醚
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21152-20mg |
分析标准品,HPLC≥98% |
¥200.00 |
现货 |
|
YJ-B21152-100mg |
分析标准品,HPLC≥98% |
¥550.00 |
现货 |
|
JS26004-5g |
≥98% |
¥320.00 |
现货 |
|
JS26004-25g |
≥98% |
¥810.00 |
现货 |
|
JS26004-100g |
≥98% |
¥2000.00 |
2-3天 |
|
A10220-20mg |
分析标准品,含量99.8%,可溯源 |
¥330.00 |
现货 |
产品介绍
熔点:83-84℃
沸点:396.7 ℃ at 760 mmHg
外观:白色针状结晶粉末
溶解性:溶于碱溶液、甲醇、乙醇、氯仿、丙tong、醋酸*乙酯和沸石油mi等,不溶于水和石油mi。
储存条件:2-8℃
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- 作者
- 内容
- 询问日期
文献和实验参考文献(42篇)
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38. [IF=5.6] Qiangsheng Li et al."Osthole ameliorates early diabetic kidney damage by suppressing oxidative stress, inflammation and inhibiting TGF-β1/Smads signaling pathway."INTERNATIONAL IMMUNOPHARMACOLOGY".2024 May;133:112131
37. [IF=1.3] NAEEM MUHAMMAD et al."Preparation, optimization and evaluation of Osthole transdermal therapeutic system."ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS.2023 Dec;95:e20221023
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33. [IF=3.4] Zhen Ma et al."Identification of chemical compounds of Schizonepeta tenuifolia Briq. and screening of neuraminidase inhibitors based on AUF-MS and SPR technology."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024 Jan;237:115787
32. [IF=3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683
31. [IF=4.927] Zhe Ma et al."Osthole Alleviates D-Galactose-Induced Liver Injury In Vivo via the TLR4/MAPK/NF-κB Pathways."MOLECULES.2023 Jan;28(1):443
30. [IF=6.208] Xiuyun Li et al."UPLC-Q-TOF/MS-Based Metabolomics Approach Reveals Osthole Intervention in Breast Cancer 4T1 Cells."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(2):1168
29. [IF=1.698] Mengjie Xue et al."Illumination on Chemical Compounds from Qufeng Zhitong Capsule and Its Potential Pharmacological Mechanism against Rheumatoid Arthritis Based on UHPLC/Q-Orbitrap-MS Combined with Network Pharmacology Analysis."International Journal of A
28. [IF=3.318] Zhenhua Tian et al."Affinity ultrafiltration and UPLC-HR-Orbitrap-MS based screening of neuraminidase inhibitors from Angelica pubescens."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Oct;1208:123398
27. [IF=2.594] Xue Mengjie et al."Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds."Journal of Analytical Methods in Chemistry.2022;2022:4229945
26. [IF=4.566] Li Ruili et al."Integrated 16S rRNA Gene Sequencing and Metabolomics Analysis to Investigate the Important Role of Osthole on Gut Microbiota and Serum Metabolites in Neuropathic Pain Mice."Front Physiol. 2022 Feb;0:35
25. [IF=1.663] Wei Huang et al."Effects of osthol on activity, mRNA and protein expression of Cyp3a in rats in vivo."Biopharm Drug Dispos. 2020 Feb;41(1-2):64-71
24. [IF=1.813] Chen Xi et al."Antipruritic Effect of Ethyl Acetate Extract from Fructus cnidii in Mice with 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis."Evid-Based Compl Alt. 2020;2020:6981386
23. [IF=2.629] Yang Niuniu et al."Desensitization of TRPV1 Involved in the Antipruritic Effect of Osthole on Histamine-Induced Scratching Behavior in Mice."Evid-Based Compl Alt. 2021;2021:4012812
22. [IF=3.263] Jing Liang et al."Osthole inhibits ovarian carcinoma cells through LC3-mediated autophagy and GSDME-dependent pyroptosis except for apoptosis."Eur J Pharmacol. 2020 May;874:172990
21. [IF=4.162] Guijie Li et al."Characterization of Oxygenated Heterocyclic Compounds and in vitro Antioxidant Activity of Pomelo Essential Oil."Drug Des Dev Ther. 2021; 15: 937–947
20. [IF=4.52] Muhammad Waqas et al."Osthole: A Coumarin Derivative Assuage Thiram-Induced Tibial Dyschondroplasia by Regulating BMP-2 and RUNX-2 Expressions in Chickens."Antioxidants-Basel. 2019 Sep;8(9):330
19. [IF=4.831] Ruili Li et al."Osthole alleviates neuropathic pain in mice by inhibiting the P2Y1-receptor-dependent JNK signaling pathway."Aging-Us. 2020 May 15; 12(9): 7945–7962
18. [IF=5.753] Liu Man et al."Constructing a Core Collection of the Medicinal Plant Angelica biserrata Using Genetic and Metabolic Data."Front Plant Sci. 2020 Dec;0:2099
17. [IF=3.246] Sun Chaojie et al."Preparation and Pharmacokinetics Evaluation of Solid Self-Microemulsifying Drug Delivery System (S-SMEDDS) of Osthole."Aaps Pharmscitech. 2018 Jul;19(5):2301-2310
16. [IF=4.411] Liang Yang et al."New Insights into the Antibacterial Activity of Hydroxycoumarins against Ralstonia solanacearum."Molecules. 2016 Apr;21(4):468
15. [IF=7.514] Gui-Jie Li et al."Determination of citrus juice coumarins, furanocoumarins and methoxylated flavones using solid phase extraction and HPLC with photodiode array and fluorescence detection."Food Chem. 2019 Jan;271:29
14. Yang, Yan-Fang, Lei Zhang, and Xiu-Wei Yang. "Distribution assessments of coumarins from Angelicae Pubescentis Radix in rat cerebrospinal fluid and brain by Liquid Chromatography Tandem Mass Spectrometry analysis." Molecules 23.1 (2018): 225.https:##doi.or
13. Chen, Xi, et al. "Antipruritic effect of ethyl acetate extract from fructus cnidii in mice with 2, 4-dinitrofluorobenzene-induced atopic dermatitis." Evidence-Based Complementary and Alternative Medicine 2020 (2020).https:##doi.org/10.1155/2020/6981386
12. Jing Liang, Jianlong Zhou, Youqin Xu, Xiaofei Huang, Xuefei Wang, Wenhua Huang, Hui Li, Osthole inhibits ovarian carcinoma cells through LC3-mediated autophagy and GSDME-dependent pyroptosis except for apoptosis, European Journal of Pharmacology, Volume 87
11. Waqas M, Wang Y, Li A, Qamar H, Yao W, Tong X, Zhang J, Iqbal M, Mehmood K, Li J. Osthole: A Coumarin Derivative Assuage Thiram-Induced Tibial Dyschondroplasia by Regulating BMP-2 and RUNX-2 Expressions in Chickens. Antioxidants. 2019; 8(9):330. https:##do
10. Huang, Wei, et al. "Effects of osthol on activity, mRNA and protein expression of Cyp3a in rats in vivo." Biopharmaceutics & drug disposition 41.1-2 (2020): 64-71.https:##doi.org/10.1002/bdd.2214
9. Huang, Wei, et al. "Effects of osthol on activity, mRNA and protein expression of Cyp3a in rats in vivo." Biopharmaceutics & drug disposition 41.1-2 (2020): 64-71.https:##doi.org/10.1002/bdd.2214
8. 庞雯辉,赵希娟,陈西,张耀海,王成秋,赵其阳,焦必宁.超高效液相色谱-四极杆-飞行时间高分辨质谱法快速筛查柠檬果实中的生物活性成分[J].食品与发酵工业,2021,47(04):222-230+235-237.
7. 张珊.蛇床子素对慢性不可预见性应激抑郁模型大鼠对炎症因子及行为学的影响[J].中医临床研究,2020,12(25):25-28.
6. 王雪莲, 李敏敏, 胡军华,等. 18种香豆素类化合物对柑桔炭疽菌的抑制作用[J]. 中国南方果树, 2013, 42(004):73-74.
5. 高学成 仝燕. 冬青油促进蛇床子素和桅子苷透皮吸收的研究[J]. 中国中药杂志 2017 042(007):1338-1343.
4. 杨宁辉, 付金芳, 曹伶俐. 蛇床子素渗透泵控释片制备工艺的优化及其体外释药行为[J]. 中成药, 2018, 040(009):1954-1958.
3. 王青, 张云, 毛红娇, et al. 蛇床子素对TCP颗粒诱导小鼠颅骨溶解的影响[J]. 中国病理生理杂志, 2015, 31(12):2265-2270.
2. 刘畅, 吴娜, 田甜,等. 蛇床子素体外抗犬源蓝氏贾第鞭毛虫作用研究[J]. 中国病原生物学杂志, 2013, 008(011):1014-1016.
1. 李文超, 2], 顾有方,等. 蛇床子素体外对蓝氏贾第鞭毛虫超微结构的影响[J]. 中国寄生虫学与寄生虫病杂志, 2014, 32(3):19-242.
摘要:对五因素间的交互作用进行考察,确定超临界CO2萃取的最佳工艺参数。方法采用二次回归连贯设计的方法。结果P萃与T分Ⅰ之间的交互作用较为明显,T分Ⅰ与T分Ⅱ之间的交互作用次之,T萃与T分Ⅰ、T萃与P分Ⅰ,P分Ⅰ与T分Ⅱ之间的交互作用对蛇床子素提取率有一定影响。优化的工艺条件为:萃取压力为40 MPa,萃取温度40℃;分离Ⅰ温度45℃;分离Ⅱ压力为5 MPa,分离Ⅱ温度为46℃;CO2流量为18 L/h,萃取时间为80 min,在此条件下,蛇床子素提取率可达4.32%。结论采用二次
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