- ￥1500 - 4500
- MedChemExpress(MCE)
- 美国
- HY-16363
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
4°C, stored under nitrogen
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
195883-06-8
- 规格：
1 mg/5 mg
| 规格： | 1 mg | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥4500.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Omtriptolide
CAS No. : 195883-06-8
MCE 国际站：Omtriptolide
产品活性：Omtriptolide (PG490-88) 是从中草药纯化的雷公藤内酯的衍生物前体。
研究领域：MAPK/ERK Pathway | Stem Cell/Wnt
作用靶点：ERK
In Vitro: Triptolide, a traditional Chinese medicine, has anti-inflammatory, antiproliferative, and proapoptotic properties.
In Vivo: In a mouse model of cisplatin-induced AKI, omtriptolide results in a significant decrease in blood urea nitrogen (BUN), serum creatinine, and acute tubular necrosis (ATN) score, and a nonsignificant increase in tubular apoptosis score in AKI. The protection of omtriptolide against AKI is associated with a decrease in p-ERK and is independent of MKP-1 and proinflammatory cytokines. In a mouse heterotopic tracheal allograft model of obliterative airway disease, omtriptolide attenuates airway obliteration and inhibits accumulation of inflammatory cells, and therefore may have preventive or therapeutic benefits for patients with obliterative airway disease following lung transplantation. Omtriptolide inhibits fibrosis in the bleomycin group when given the same day or 5 days after bleomycin. Omtriptolide also markedly reduces the number of myofibroblasts in the bleomycin treatment group. Omtriptolide inhibits in vivo both CD4+Vbeta3+ and CD8+Vbeta3+ T cell (alloreactive T cells in this model) expansion in the spleen by 64.09 and 34.02%, respectively, at the time when Vbeta3+ cell expansion is in the logarithmic phase (day 3 after transplantation).
相关产品：Bioactive Compound Library Plus | PD98059 | Yoda 1 | SCH772984 | TBHQ | Tauroursodeoxycholate | Ulixertinib | Honokiol | Astragaloside IV | Piperlongumine | Ravoxertinib | Temuterkib | C16-PAF | Lidocaine | FR 180204 | BIX02189 | XMD8-92 | MK-8353 | 6-OAU | Patritumab | trans-Zeatin | SEW2871 | Urolithin B | VX-11e | ASN007 | Pamoic acid | Pachymic acid | AG126 | Lysophosphatidylcholines
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
