COX-2-IN-1,787623-48-7

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COX-2-IN-1

CAS No. : 787623-48-7

MCE 国际站：COX-2-IN-1

产品活性：COX-2-IN-1 是 一个强效的 COX-2 抑制剂，其 IC₅₀ 值为 3.9 μM。

研究领域：Immunology/Inflammation

作用靶点：COX

In Vitro: COX-2-IN-1(compound 5f) is an inhibitor of COX-1 and COX-2 with IC₅₀s of >100 and 3.9 μM, respctively. Comparison of 5b and COX-2-IN-1 shows that smaller halogen atom at 5th position on the indole ring enhances COX-2 enzyme inhibition activity, whereas the presence of a larger bromine atom at 6th position of the ring improves the inhibitory activity (5d, 5e and 5h) of the compound.

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