Resistin-like beta, Cysteine-rich secreted protein FIZZ2
Description :
Human RELM-β is a 19.0 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELM-β and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly the molecular structure of RELM-β is highly homologous to that of the adipose-derived cytokine Resistin and RELM-α. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11 -C-X8 -C-X-C-X3 -C-X10 -C-X-C-X-C-X9 -C-C. Recombinant Human RELM-β is a disulfide-linked homodimer with a total molecular weight of 19.0 kDa, consisting of two 89 amino acid residue chains.
Catalog #:
450-22
Source :
E.coli
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).