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- PeproTech
- 350-09
- 美国
- 2025年12月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 供应商：
PeproTech(派普泰克)
- 英文名：
Recombinant Human IGF-Binding Protein 7
| Synonyms : |
Insulin-like growth factor binding protein-7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBPrP1) |
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| Description : |
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 257 amino acid residues. |
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| Catalog #: |
350-09 |
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| Source : |
E.coli |
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| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses |
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| Endotoxin Level : |
Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
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| Biological Activity : |
Testing In Progress. |
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| AA Sequence : |
MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TELLPGDRDN LAIQTRGGPE KHEVTGWVLV SPLSKEDAGE YECHASNSQG QASASAKITV VDALHEIPVK KGEGAEL |
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| PubMed Link : |
IGF+AND+Binding+AND+Protein+AND+7 |
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| Country of Origin : |
USA |
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PeproTech重组人IGF-BP7参考文献链接：
http://www.peprotech.com/en-US/Pages/References/350-09
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