IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Catalog #:
217-17
Source :
E.coli
Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.