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- 技术资料
- 供应商:
PeproTech(派普泰克)
- 库存:
大量
- 英文名:
Recombinant Murine IL-10
| Synonyms : |
B-TCGF, CSIF, TGIF |
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| Description : |
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues. |
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| Catalog #: |
210-10 |
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| Source : |
E.coli |
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| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
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| Endotoxin Level : |
Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
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| Biological Activity : |
's murine IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells. The ED50 was found to be < 2 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. |
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| Selected References : |
Selected List of References Citing This Product |
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| AA Sequence : |
MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S |
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| PubMed Link : |
IL-10+AND+mouse |
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| Country of Origin : |
USA |
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Usage: |
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