Belizatinib,1357920-84-3

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Belizatinib

CAS No. : 1357920-84-3

MCE 国际站：Belizatinib

产品活性：Belizatinib 是一种有效的，可口服的ALK 和 TRKA、TRKB、TRKC 双重抑制剂，对野生型重组 ALK 的 IC₅₀ 值为0.7 nM。

研究领域：Protein Tyrosine Kinase/RTK  |  Neuronal Signaling

作用靶点：Anaplastic lymphoma kinase (ALK)  |  Trk Receptor

In Vitro: TSR-011 has antitumour activity in the clinical trials.

In Vivo: TSR-011 exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models.

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