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C-Peptide (Rat)

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  • ¥600 - 1500
  • Abbiotec已认证
  • 美国
  • 350593
  • 2025年07月10日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 注册证号

      见详细说明书

    • 保存条件

      Store at -20°C.

    • 保质期

      1-2年

    • 英文名

      C-Peptide (Rat)

    • 库存

      一定量库存

    • 供应商

      华拓生物(中国代理)

    • 规格

      1

    产品细节图片1
    产品名称: C-Peptide (Rat)
    产品链接: http://abbiotec.com/peptides/c-peptide-rat
    货号: 350593
    规格: 1 mg
    产品描述: The connecting peptide, or C-peptide, is a 31-aa long peptide that connects insulin A-chain to the B-chain in the proinsulin molecule. In the insulin synthesis pathway, preproinsulin is translocated into the endoplasmic reticulum of beta cells of the pancreas with an A-chain, a C-peptide, a B-chain, and a signal sequence. After signal sequence cleavage, the C-peptide is removed from the newly formed proinsulin in the Golgi apparatus leaving the A- and B-chains bound together by disulfide bonds, forming the insulin molecule. Besides a role in assembly, folding, and processing of insulin in the ER, the C-peptide is a bioactive peptide with effects on microvascular blood flow and tissue health. Because equimolar amounts of C-peptide are stored in secretory granules of the pancreatic beta cells and eventually released in the circulation, C-peptide is a marker of insulin secretion in understanding the pathophysiology of type 1 and type 2 diabetes. Rodents express 2 nonallelic genes of insulin. Insulin-2 is the rodent homologue of the human insulin. Insulin-1 lacks the second intron of the insulin-2 gene.
    序列: Rat: H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH or H-EVEDPQVPQLELGGGPEAGDLQTLALEVARQ-OH
    分子式: C140H228N38O51
    分子量: 3260.84 g/mol
    纯度: Purity > 95% by HPLC
    别名: C-peptide; insulin-1; INS1; insulin
    形态: Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
    溶解方法: Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
    保存方法: Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.

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