RS-601,207987-59-5

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RS-601

CAS No. : 207987-59-5

MCE 国际站：RS-601

产品活性：RS-601 是有效的 leukotriene D4/thromboxane A2 双重抑制剂，具有平喘作用。

研究领域：GPCR/G Protein

作用靶点：Leukotriene Receptor  |  Prostaglandin Receptor

In Vivo: RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR.

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