SM-6586,103898-38-0

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SM-6586

CAS No. : 103898-38-0

MCE 国际站：SM-6586

产品活性：SM-6586 是一种 calcium channel 的拮抗剂，同时能够抑制 Na⁺/H⁺ 和 Na⁺/Ca²⁺ exchange transport，主要用于研究脑血管疾病和高血压等疾病。

研究领域：Membrane Transporter/Ion Channel  |  Neuronal Signaling

作用靶点：Calcium Channel  |  Na+/Ca2+ Exchanger

In Vivo: In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group.

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