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- 2025年12月05日
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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期：询盘
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MedChemExpress LLC
- CAS号：
103898-38-0
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1 mg///5 mg
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SM-6586
CAS No. : 103898-38-0
MCE 国际站：SM-6586
产品活性：SM-6586 是一种 calcium channel 的拮抗剂，同时能够抑制 Na+/H+ 和 Na+/Ca2+ exchange transport，主要用于研究脑血管疾病和高血压等疾病。
研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling
作用靶点：Calcium Channel | Na+/Ca2+ Exchanger
In Vivo: In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group.
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文献和实验-8. Yuan XB, Jin M, Xu X, Song YQ, Wu CP, Poo MM and Duan SM (2003). Signaling and crosstalk of rho-GTPases in mediating axon guidance. Nature Cell Biology , 5: 38-45. Wang B, Xiao Y, Ding BB, Zhang N, Yuan X, Gui L, Qian KX, Duan S, Chen Z, Rao Y
without agitation for 20 min to 1 hr. Plate as 100 ul aliquots onto LB Amp50 Kan40 Cm34. Grow 1-2 days at 30oC. Now have cointegrates. (Set up strain R1230 in Sm50 overnight). Mate to strain R1230 to resolve cointegrates
the starting strains onto this media. Grow 1-2 days at 30o C. Now you have cointegrates. Set up strain #70/B425 in Sm50 Cm34 overnight. Resolve cointegrates by mating to strain #70/B425. Elute colonies
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