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- MedChemExpress(MCE)
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- 2025年12月05日
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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期：询盘
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MedChemExpress LLC
- CAS号：
101189-47-3
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1 mg
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CP-66948
CAS No. : 101189-47-3
MCE 国际站：CP-66948
产品活性：CP-66948 是 histamine H2 受体拮抗剂，能够抑制胃酸分泌，保护粘膜的作用。
研究领域：GPCR/G Protein | Neuronal Signaling | Immunology/Inflammation
作用靶点：Histamine Receptor
In Vivo: The affinity of CP-66,948 for the guinea pig atria histamine H2-receptor is 15 times greater than that of cimetidine and seven times greater than that of ranitidine. In vivo, the ED50 value for inhibition of gastric acid secretion in pylorus-ligated rats is 2 mg/kg intraduodenally, and in histamine or pentagastrin-stimulated Heidenhain pouch dogs the antisecretory ED50 values are 0.3 mg/kg per os and 1.0 mg/kg per os, respectively. CP-66,948 also inhibits ethanol-induced gastric hemorrhagic lesions in rats following either oral or systemic administration (ED50 values of 12 mg/kg per os and 6 mg/kg subcutaneously).
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文献和实验Isolation of CP43 and CP47 Photosystem II Proximal Antenna Complexes From Plants
A single-column method to purify the CP43 and CP47 pigment-protein complexes of photosystem (PS)II from higher plants is presented. To validate the isolation procedure, three different species were used (Spinacea oleracea, Beta vulgaris
Isolation and Purification of CP43 and CP47 Photosystem II Proximal Antenna Complexes from Plants
A method to isolate and purify CP43 and CP47 pigment–protein complexes from Photosystem (PS) II of higher plants is presented. The method has been developed in spinach, but it may also be valid for other plant species, since there is high
的捕获（light-harvesting）、电子的分离以及分子氧的产生（oxygen evolution）。PSⅡ是一个广泛存在于植物、藻类及蓝细菌中的类囊体膜上的色素蛋白复合体，它能够驱动被光激活的电子从水向质体醌传递，并伴随分子氧的产生。PSⅡ是一个由多个亚基组成的色素蛋白大分子复合体，共由20多个多肽组成，包括反应中心复合体（D1、D2蛋白和Cyt b559等）、叶绿素集光蛋白（CP47、CP43）、外周叶绿素集光蛋白（LHC II）、3个与放氧有关的外周多肽（33kD、24kD、18kD
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