Recombinant Human Glutaminase

Introduction of human 14-3-3 proteins

The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14

In Vitro Identification of UDP-Glucuronosyltransferases (UGTs) Involved in Drug Metabolism

in the prediction of adverse reactions resulting from drug-drug interactions or genetic polymorphism. An integrated approach is proposed for UGT reaction phenotyping using recombinant enzymes and human liver microsomes. Described methods include screening

In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism

for the prediction of adverse reactions caused by drug–drug interactions or individual genetic polymorphism. An integrated approach is described for CYP-mediated metabolic reaction phenotyping using both recombinant enzymes and human liver microsomes in combination