Recombinant rat Alpha-2-macrog

Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy

is a cardiac isoform of α2 -macroglobulin belonging to the macro-globulin family. Furthermore, it has been demonstrated that direct injection of the purified 182-kDa protein intravenously (through the tail vein) into the normal animals led to the development

Local Gene Delivery of Recombinant Adenoviruses to the Rat Carotid Artery In Vivo

, where recurrence of a stenosis occurs in an abnormal blood vessel treated by angioplasty. The main animal models used to study vascular balloon injury or angioplasty are the rat carotid, the rabbit iliac, the pig coronary and carotid models, and, less frequently

Use of Recombinant Adenovirus for Gene Transfer into the Rat Brain: Evaluation of Gene Transfer Efficiency, Toxicity, and Inflammatory and Immune Reac

Adenovirus (Ad) vectors have been used to successfully deliver genes into a wide variety of non-central nervous system (CNS) tissues and organs in animal models of human disease and in several human phase I clinical trials (1 –