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文献和实验Engineering Bioactive Peptide-Based Therapeutic Molecules
desired physicochemical and in vivo properties. In this chapter, we describe a general methodology of identifying bioactive peptides by biopanning of peptide phage libraries. As an example of therapeutic peptide modifications, we also describe a method
Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC
on the function of antibody molecules is also a regulatory requirement. Glycan mapping by NP-HPLC with fluorescence detection is a sensitive and reproducible method. Labeling of released glycans with anthranilic acid (AA) using reductive amination procedure
A Method for the Rapid Identification of Epitopes and Other Functional Peptide Domains
can be of major importance in the development of vaccines and other pharmaceutical compounds.
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