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- 2026年01月17日
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文献和实验Anti-c-erb-B-2 Ribozyme for Breast Cancer
Our laboratory has investigated the cleavage activity of an-anti-c-erb -B-2 ribozyme. The c-erb -B-2 proto-oncogene (also called HER-2/neu ) encodes a 185 kDa transmembrane tyrosine kinase-type receptor that is homologous with the epidermal
Anti-c-erb1B2 Ribozyme for Gene Therapy of Breast Cancer
The application of antioncogene ribozyme in the gene therapy of breast cancer by means of recombinant adenoviral vector is dicussed in this chapter. We have shown that recombinant adenovirus encoding anti-cerbB2 ribozyme inhibited the breast
Developing Anti-HER2/neu Single-Chain Fv Fragments from Phage Display Libraries
effects strictly to malignant cells. The notable exception has been in the treatment of B-cell lymphomas that have exhibited an exciting response rate when treated with unconjugated (2 ) and radiolabeled (3 ) MAbs. However, similar progress
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