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文献和实验ORDERING INFORMATION Catalog Number: HAF007 Lot Number: FIM06 Size: 1 mL Formulation: 0.2 μm filtered solution in PBS with stabilizers Storage: 2 - 8° C Specificity: mouse IgG1, mouse IgG2A, mouse IgG2B, mouse IgG3 heavy and light chains Immunogen
Methods to Engineer and Identify IgG1 Variants with Improved FcRn Binding or Effector Function
site comprised of the heavy and light chain variable domains. In addition, the Fc portion of human or humanized IgG1 antibodies promotes long half-life through interaction with the recycling FcRn receptor and effects killing functions
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
++++ ++++ Mouse IgG2b +++ +++ Mouse IgG3 ++ +++ Rat IgG1 - + Rat IgG2a - ++++ Rat IgG2b - ++ Rat IgG2c
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