- ￥7984
- American Research Products
- 21-1287-1 ml
- 2026年01月01日
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文献和实验Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE
to anaphylaxis. Here, we describe the history behind the IgE discovery and the protocol for purifying IgE and anti-IgE in the mouse. This is followed by our ELISA protocol for mouse IgE detection.
Measuring Allergen-Specific IgE: Where Have We Been and Where Are We Going
forward the science of allergy was greatly advanced. Within a few years of the IgE discovery, an assay for IgE was developed. This test was named the radio allergosorbent test. The specific IgE testing methodology has matured in the last four decades
IgE 与高亲和力IgE 受体 IgE主要由鼻咽、扁桃体、支气管、胃肠等处黏膜固有层中的浆细胞产生，这些部位也是变应原侵入并引起过敏反应的好发部位。IgE受体(FcεR)有两种类型：一类为高亲和力受体，即FcεR I(解离常数达1X10-10 M)，此类受体与Fc结合后的稳定性远高于其他Fc受体；另一类为低亲和力受体，称为FcεRⅡ，它和IgE结合的亲和力比FcεR1低100～1 000倍。研究发现FcεR I还有两个异构体，分别表达于IL-4刺激过的B细胞、单核细胞和嗜
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