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文献和实验Analysis of Anti-Interferon Properties of the Herpes Simplex Virus Type I ICP0 Protein
A defining hallmark of the type 1 interferons (IFNs) is their ability to interfere with virus replication. As such, viruses have evolved diverse mechanisms to subvert the antiviral effects of interferons. Herpes simplex virus type 1 (HSV
Generation of Recombinant Herpes Simplex Virus Ampiicons
The herpes simplex virus type 1 (HSV-1) amphcon has been developed as a novel eukaryotic expression vector, which contains an HSV-1 ori for DNA replication and a pac signal for cleaving/packaging genomes into viral
Delivery Using Herpes Simplex Virus: An Overview
to persist in a lifelong nonintegrated latent state without causing disease in the immune-competent host. Among the herpesviruses, herpes simplex virus type 1 (HSV-1) is an attractive vehicle because in natural infection, the virus establishes latency
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