Reconstitute in PBS or others. Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
英文名:
AIM2
规格:
10 ug
NCBI Gene Id: 9447
Swissprot Id: O14862
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8. Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OPCD01224
SDS-PAGE
AIM2 Recombinant Protein (OPCD01224) using SDS-PAGE