NCBI Gene Id: 3566
Swissprot Id: P24394
IL4 can signal through type I and type II receptor complexes, which share a common gamma chain (gammac). The type I receptor contains in addition to the gamma chain an IL4Ralpha subunit, whereas the type II receptor contains the IL13Ralpha. The secreted extracellular domain of IL4Ralpha, called sIL4Ralpha, binds IL4 and antagonizes its activity. It plays an important role in regulating the differentiation of naive CD4 T cells and class switching to IgG1 and IgE. Recombinant human sIL4Ralpha is a 209 amino acid protein which corresponds to the entire extracellular domain of IL4Ralpha. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OPBG00008
Interleukin-4 Receptor Subunit Alpha SDS-PAGE
IL4R Recombinant Protein (Human) (OPBG00008) using SDS-PAGE