NCBI Gene Id: 5742
Swissprot Id: P23219
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN02232
Human Liver
Immunohistochemistry of paraffin-embedded human liver cancer using PTGS1 antibody at dilution of 1:100 (40x lens).
Multiple Cell Lines
Western blot analysis of extracts of various cell lines, using PTGS1 antibody.