NCBI Gene Id: 51135
Swissprot Id: Q9NWZ3
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN01656
Multiple Cell Lines
Western blot analysis of extracts of various cell lines, using IRAK4 antibody.