A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser319/S323 of human IL10RA
规格:
50ul
NCBI Gene Id: 3587
Swissprot Id: Q13651
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN03005
HeLa Cells
Western blot analysis of extracts from HeLa cells, using Phospho-IL10RA-S319/S323 antibody.