A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Thr45 of human EIF4EBP1
规格:
50ul
NCBI Gene Id: 1978
Swissprot Id: Q13541
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN02860
Human Breast
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-EIF4EBP1-T45 antibody.
HeLa Cells
Western blot analysis of extracts from Hela cells using Phospho-EIF4EBP1-T45 antibody.