A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser49 of human EIF2S1
规格:
50ul
NCBI Gene Id: 1965
Swissprot Id: P05198
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010] - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN02976
HeLa Cells
Immunofluorescence staining of methanol-fixed Hela cells using phospho-EIF2S1-S49 antibody.
Human Breast
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using phospho-EIF2S1-S49 antibody.
HeLa Cells
Western blot analysis of extracts from Hela cells, using phospho-EIF2S1-S49 antibody.