Store at -20°C. Avoid repeated freeze/thaw cycles.
形态:
<b>Liquid.</b> PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
亚型:
IgG
免疫原:
Recombinant protein of human CYP19A1
规格:
50ul
NCBI Gene Id: 1588
Swissprot Id: P11511
CYP19A1(Cytochrome P450 19A1) is also named as ARO1(aromatase), CYAR, CYP19, estrogen synthase and belongs to the cytochrome P450 family. It is a terminal enzyme which transforms irreversibly androgens into estrogens and it is present in the endoplasmic reticulum of numerous tissues(PMID:16406261). The gene encodes a protein with the molecular weight between 46 kDa and 69 kDa(PMID:8129748) and the protein can be glycosylated, but the level of glycosylation does not seem to be essential for CYP19A1 activity(PMID:12606587). Brain aromatase may be neuroprotective by increasing the local estrogen levels in injured neurons so that genetic variation in the brain aromatase gene may modify the risk for AD(PMID:16767510). This antibody is specific to CYP19A1. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAN00762
Multiple Cell Lines
Western blot analysis of extracts of various cell lines, using CYP19A1 antibody.