For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
形态:
Liquid, 1 mg/mL provided in PBS containing 0.02% sodium azide.
亚型:
IgG
免疫原:
TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L.
规格:
100 ug
NCBI Gene Id: 25789
Swissprot Id: Q9UK28
TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAPB01456
Heart tissue lysate
Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/mL.