E.coli-derived mouse NF-kB p65 recombinant protein (Position: D291-Q479). Mouse NF-kB p65 shares 77% amino acid (aa) sequence identity with human NF-kB p65.
规格:
100 ug
NCBI Gene Id: 19697
Swissprot Id: Q04207
Transcription factor p65, also known as NFKB3 or NF-kB p65, is a protein encoded by the RELA gene. NFKB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system. Phosphorylation and acetylation of NFKB3 are crucial post-translational modifications required for NFKB activation. It has also been shown to modulate immune responses, and activation of NFKB3 is positively associated with multiple types of cancer. In addition to that, NFKB3 antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABB01807
Anti-NF-kB p65 Picoband antibody, OABB01807, Western blotting All lanes: Anti NF-kB p65 (OABB01807) at 0.5ug/mlg Lane 1: PC 12 Whole Cell Lysate at 40ug Lane 2: NRK Whole Cell Lysate at 40ug Lane 3: HEPA Whole Cell Lysate at 40ug Lane 4: NIH Whole Cell Lysate at 40ug Predicted bind size: 65KD Observed bind size: 65KD