E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.
规格:
100 ug
NCBI Gene Id: 6506
Swissprot Id: P43004
SLC1A2 is also known as EAAT2 or GLT-1. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABB02116
Anti-EAAT2 antibody, OABB02116, Western blotting All lanes: Anti EAAT2 (OABB02116) at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Mouse Brain Tissue Lysate at 50ug Lane 3: U87 Whole Cell Lysate at 40ug Lane 4: SMMC Whole Cell Lysate at 40ug Lane 5: PANC Whole Cell Lysate at 40ug Lane 6: A549 Whole Cell Lysate at 40ug Predicted bind size: 62KD Observed bind size: 62KD