A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2 (413-447aa KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR), identical to the related mouse and rat sequences.
规格:
100 ug
NCBI Gene Id: 3418
Swissprot Id: P48735
Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABB02085
Human Intestinal Cancer Tissue
Anti-IDH2 Picoband antibody, OABB02085, IHC(P) IHC(P): Human Intestinal Cancer Tissue
Anti-IDH2 Picoband antibody, OABB02085, IHC(P) IHC(P): Rat Intestine Tissue
Rat Cardiac Muscle Tissue Lysate, Rat Liver Tissue Lysate, NIH3T3 Whole Cell Lysate, SW620 Whole Cell Lysate, HELA Whole Cell Lysate, MCF-7 Whole Cell Lysate, 22RV1 Whole Cell Lysate
Anti-IDH2 Picoband antibody, OABB02085, Western blotting All lanes: Anti IDH2 (OABB02085) at 0.5ug/ml Lane 1: Rat Cardiac Muscle Tissue Lysate at 50ug Lane 2: Rat Liver Tissue Lysate at 50ug Lane 3: NIH3T3 Whole Cell Lysate at 40ug Lane 4: SW620 Whole Cell Lysate at 40ug Lane 5: HELA Whole Cell Lysate at 40ug Lane 6: MCF-7 Whole Cell Lysate at 40ug Lane 7: 22RV1 Whole Cell Lysate at 40ug Predicted bind size: 51KD Observed bind size: 51KD