Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
形态:
Liquid. 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
亚型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.
规格:
100 ul
NCBI Gene Id: 5653
Swissprot Id: Q92876
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAGA02312
Paraformaldehyde-fixed U2OS
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed U2OS, using Kallikrein 6 (OAGA02312) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled (Red) at 1:2000.