Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
形态:
Liquid. 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
亚型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human CDK6. The exact sequence is proprietary.
规格:
100 ul
NCBI Gene Id: 1021
Swissprot Id: Q00534
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAGA02236
Paraformaldehyde-fixed Hela
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CDK6 (OAGA02236) antibody at 1:200 dilution.
Human colon carcinoma
CDK6 antibody [N1C3] detects CDK6 protein at cytoplasm and nucleus on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. CDK6 antibody [N1C3] (OAGA02236) diluted at 1:500.
Hela
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE OAGA02236 diluted at 1:1000