Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
形态:
Liquid. 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
亚型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human Cyclin D3. The exact sequence is proprietary.
规格:
100 ul
NCBI Gene Id: 896
Swissprot Id: P30281
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAGA01626
Paraformaldehyde-fixed A431
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Cyclin D3 (OAGA01626) antibody at 1:500 dilution.
Mouse lung
Cyclin D3 antibody detects Cyclin D3 protein at membrane on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. Cyclin D3 antibody (OAGA01626) dilution: 1:500.