Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
形态:
Liquid. 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
亚型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Cortactin. The exact sequence is proprietary.
规格:
100 ul
NCBI Gene Id: 2017
Swissprot Id: Q14247
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAGA01221
Paraffin-embedded Breast ca
Immunohistochemical analysis of paraffin-embedded Breast ca, using Cortactin (OAGA01221) antibody at 1:250 dilution.
HepG2
Sample (30 ug of whole cell lysate) A: Hep G2 7.5% SDS PAGE OAGA01221 diluted at 1:1000
NIH-3T3
Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC 7.5% SDS PAGE OAGA01221 diluted at 1:1000
PC-12
Sample (30 ug of whole cell lysate) A: PC-12 7.5% SDS PAGE OAGA01221 diluted at 1:3000