KLH conjugated synthetic peptide derived from human KLK6
规格:
100 ul
NCBI Gene Id: 5653
Swissprot Id: Q92876
Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OABF01617
Rat lung
Formalin-fixed and paraffin embedded rat lung labeled with Anti KLK6 Polyclonal Antibody, Unconjugated (OABF01617) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Human colon carcinoma tissue
Formalin-fixed and paraffin embedded human colon carcinoma tissue labeled with Anti KLK6 Polyclonal Antibody, Unconjugated (OABF01617) at 1:200 followed by conjugation to the secondary antibody and DAB staining.