The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
亚型:
Rabbit IgG
免疫原:
A synthetic peptide derived from the C-term of Human Cyclin C. This sequence is identical to Human, Mouse, Rat.
规格:
100 ug
NCBI Gene Id: 892
Swissprot Id: P24863
The Cyclin C is highly conserved protein that is involved in divergent cellular processes. This protein interacts with cylin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Cyclin C is a critical regulator of the G(0)/G(1) transition of the Human stem cell. There are two isoforms cyclin C1 and Cyclin C2, most likely the C2 isoform may play an important role in mammalian cells and probably this isoform is the one that is mainly implicated in cell cycle regulation. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAI00305
Human Breast carcinoma
IHC: Human breast carcinoma tissue was stained with Rabbit anti -Cyclin C antibody (Cat#OAAI00305) at 1:100 for 10 min @ RT. Staining of formalin -fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
MCF -7
Western Blot: The cell lysate derived from MCF -7 was immuno -blotted by Rabbit anti Cyclin C (Cat#OAAI00305) at 1:500. An immunoreactive band around 34kDa is observed.