The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
亚型:
Rabbit IgG
免疫原:
A synthetic peptide corresponding to internal sequence of Human CD4 protein.
规格:
100 ug
NCBI Gene Id: 920
Swissprot Id: P01730
CD4, a single-pass type I transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is an accessory protein for MHC class-II antigen/T-cell receptor interaction, and may regulate T-cell activation, induce the aggregation of lipid rafts. Upon HIV-1 binding to the cell membrane, CD4 interacts with HIV-1 envelope polyprotein gp160 and protein Vpu with presence of HIV-1 gp120.
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