The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles.
亚型:
Rabbit IgG
免疫原:
A synthetic peptide from C-terminus of Human claudin 7 protein. This sequence is identical to Human, Rat, Mouse and bovine.
规格:
100 ug
NCBI Gene Id: 1366
Swissprot Id: O95471
The claudin superfamily consists of many structurally related proteins in Humans. These proteins, which include claudin 1 throμgh 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Claudin 7 (CLDN7) has two isoforms, a full-length form with 211 aa residues and a C-terminal truncated form with 158 aa residues. This protein is localized in the intercellular junctions of the epithelial cells of the proximal tubules of the nephrons in mammalian kidney. It is expressed in normal Human and Mouse epithelia. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAI00023
Mouse Kidney
Western Blot: The whole tissue lysates derived from mouse kidney were immunoblotted by Rabbit anti-Claudin 7 (cat#OAAI00023) at 1:500 (Lane 1). The immunoreactive band is blocked by pre-incubation of immunizing peptide (lane 2)