Store at -20C in undiluted aliquots; stable for up to one year after date of receipt. Avoid freeze/thaw cycles.
形态:
Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
免疫原:
Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat TrkB.
规格:
100 ul
NCBI Gene Id: 25054
Swissprot Id: Q63604
Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS (Soppet et al., 1991; Klein et al., 1991). Additionally, alterations in expression of TrkB have been associated with Alzheimer's disease (Ferrer et al., 1999; Chen et al., 2008). - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAPC00072
Rat synaptic membrane
Western blot of rat synaptic membrane preparation showing specific immunolabeling of the ~ 93k TrkB protein.