CRYGA Antibody - N-terminal region (ARP65008_P050)
靶点:
CRYGA
应用范围:
WB
宿主:
Rabbit
适应物种:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
克隆性:
Polyclonal
保存条件:
Add 50 ul of distilled water. Final concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
形态:
Lyophilized
免疫原:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CRYGA
规格:
50 ug
NCBI Gene Id: 1418
Swissprot Id: P11844
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet_lyophilized.php?sku=ARP65008_P050