BTBD12 antibody - N-terminal region (ARP59857_P050)
靶点:
SLX4
应用范围:
WB
宿主:
Rabbit
适应物种:
Human, Rabbit
克隆性:
Polyclonal
保存条件:
-20C
形态:
Lyophilized
免疫原:
The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD12
规格:
50 ug
NCBI Gene Id: 84464
Swissprot Id: Q8IY92
This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet_lyophilized.php?sku=ARP59857_P050