MAP4K4 antibody - N-terminal region (ARP49031_P050)
靶点:
MAP4K4
应用范围:
IHC, WB
宿主:
Rabbit
适应物种:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
克隆性:
Polyclonal
保存条件:
Add 50 ul of distilled water. Final concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
形态:
Lyophilized
免疫原:
The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K4
规格:
50 ug
NCBI Gene Id: 9448
Swissprot Id: O95819
MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet_lyophilized.php?sku=ARP49031_P050
Human Liver
Liver
Human Small Intestine
WB Suggested Anti-MAP4K4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human Small Intestine