Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
形态:
Liquid
亚型:
IgG3 Kappa
免疫原:
ORC6L (AAH63565, 1 a.a. ~ 252 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
规格:
100 ug
NCBI Gene Id: 23594
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAL00612
HeLa cell
Immunofluorescence of monoclonal antibody to ORC6L on HeLa cell. [antibody concentration 10 ug/ml]
ORC6L transfected lysate
Immunoprecipitation of ORC6L transfected lysate using anti-ORC6L monoclonal antibody and Protein A Magnetic Bead and immunoblotted with ORC6L MaxPab rabbit polyclonal antibody.
Transfected 293T cell line
Western Blot analysis of ORC6L expression in transfected 293T cell line by ORC6L monoclonal antibody (M04), clone 3C4. Lane 1: ORC6L transfected lysate(28.1 KDa). Lane 2: Non-transfected lysate.