Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
形态:
Liquid
亚型:
IgG2a Kappa
免疫原:
SKP1A (NP_008861, 53 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
规格:
100 ug
NCBI Gene Id: 6500
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAAL00303
HeLa cell
Immunofluorescence of monoclonal antibody to SKP1 on HeLa cell. [antibody concentration 30 ug/ml]
HeLa
SKP1A monoclonal antibody (M03), clone 2E6. Western Blot analysis of SKP1A expression in HeLa.