Human, Mouse, Rat, Bovine, Guinea Pig, Hamster, Monkey, Rabbit, Sheep
克隆性:
Monoclonal
保存条件:
<b>Long Term Storage : </b>-20C
亚型:
IgG2b
免疫原:
Horse Cytochrome c .
规格:
100 ug
NCBI Gene Id: 54205
Swissprot Id: P99999
Cytochrome c is an electron transport protein from mitochondria. A primary means of caspase activation by p53 is through induction of cytochrome c release from mitochondria. Cleavage of Bid, a Bcl 2 family member, by caspase-8 produces a truncated tBid molecule which triggers mitochondria release of cytochrome c which binds to the adaptor protein Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAED00041
Human brain, cortex tissue
IHC Analysis: Human brain, cortex tissue stained with Cytochrome c, mAb (7H8.2C12) at 5 ug/ml.
Human spleen tissue
IHC Analysis: Human spleen tissue stained with Cytochrome c, mAb (7H8.2C12) at 5 ug/ml.
Human uterus tissue
IHC Analysis: Human uterus tissue stained with Cytochrome c, mAb (7H8.2C12) at 5 ug/ml.