Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
亚型:
IgG<sup>1</sup>
免疫原:
Peptide corresponding to amino acid residues from the N-terminal region of human retinoic acid receptor, alpha -isotype.
规格:
100 ul
NCBI Gene Id: 5914
Swissprot Id: P10276
Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAPC00018
Rat hippocampal homogenate
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~48k RAR- alpha protein.