- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA773045LA01HU
- 2025年07月08日
- ELISA, IF; Recommended dilution: IF:1:50-1:200
- Rabbit
- Human
企业认证
相关产品推荐更多 >
SMAD6抗体SMAD6一抗抗体SMAD6_HUMAN antibody抗体SMAD6 Antibody抗体
￥880
MDH1抗体MDH1兔多抗抗体Soluble malate dehydrogenase antibody抗体MDH1 Antibody, Biotin conjugated抗体
￥880
/抗体/兔多抗抗体/抗体NOM1 Antibody抗体
￥2024
P2RX5抗体P2RX5一抗抗体Purinergic receptor P2X5 antibody抗体P2RX5 Antibody抗体
￥3900
TSGA10IP抗体TSGA10IP兔多抗抗体Tsga10-interacting protein antibody抗体TSGA10IP Antibody, Biotin conjugated抗体
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q86W56
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IF; Recommended dilution: IF:1:50-1:200
- 浓度：
>95%,Protein G purified
- 靶点：
PARG
- 抗体英文名：
PARG Antibody
- 抗体名：
Poly(ADP-ribose) glycohydrolase antibody
- 规格：
100μg/50μg/20μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
| 规格： | 20μg | 产品价格： | ￥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers (PubMed:23102699). Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters (PubMed:23102699). Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验poly(ADP-ribose) polymerase-1. We have been studying to analyze the mechanism of neuronal cell death observed in poly(ADP-ribose) glycohydrolase (PARG)-knockout Drosophila melanogaster that shows accumulation of polyADP-ribosylated proteins in the brain
Poly(ADP-ribosyl)ation Pathways in Mammals: The Advantage of Murine PARG Null Mutation
Studies suggest that inhibiting the hydrolysis of poly(ADP-ribose) (PAR) by targeting the enzyme PAR glycohydrolase (PARG) is a potential chemotherapeutic strategy to induce cell death. However, the lack of structural data for PARG
Poly(ADP-Ribose) Metabolism Analysis in the Nematode Caenorhabditis elegans
signaling and repair, cell death and survival, and transcription. Poly(ADP-ribose) glycohydrolase (PARG) is responsible for the specific hydrolysis of poly(ADP-ribose) (PAR), the product of poly(ADP-ribosyl)ation, and its action is required for the modified
技术资料暂无技术资料 索取技术资料
