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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human TOX high mobility group box family member 3 protein (8-305AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
HRP
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O15405
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA
- 浓度:
>95%,Protein G purified
- 靶点:
TOX3
- 抗体英文名:
TOX3 Antibody, HRP conjugated
- 抗体名:
Trinucleotide repeat containing gene 9 protein antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Real-Time RT-PCR for CTG Repeat-Containing Genes
Myotonic dystrophy (DM1) is a neuromuscular disorder caused by a CTGn expansion in the 3′-untranslated region (UTR) of myotonic dystrophy protein kinase (DMPK ). SIX5 is a homeodomain gene located just downstream of the repeat, and myotonic
Modeling and Analysis of Repeat RNA Toxicity in Drosophila
that present with similar clinical symptoms, the expansions occur in untranslated regions of the gene that cannot encode toxic peptide products. As expanded repeat-containing RNA is common to both translated and untranslated repeat
. When the HD gene was cloned in 1993, it was discovered that the causative mutation was an expansion of a CAG trinucleotide repeat (1 ) and to date HD is one of 14 trinucleotide repeat diseases (2 ). The expanded CAG sequence in exon 1 of the HD gene, IT15
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