- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA016052ESR1HU
- 2025年07月12日
- ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Nuclear receptor subfamily 2 group C member 2 protein (240-380AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P49116
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
NR2C2
- 抗体英文名：
NR2C2 Antibody
- 抗体名：
TR4 nuclear hormone receptor antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
| 规格： | 20μl | 产品价格： | ￥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5\'-AGGTCA-3\' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验) ( 2 - 4 ). The proximal promoter, containing the hormone response elements (HREs), and binding sites for nuclear factor 1 (NF1), TATA binding protein (TBP), and octamer transcription factors (OTFs) is encompassed by nucleosomes A and B ( 2 , 5 ). Analysis
and shown to contain a large variety of putative nuclear receptor genes, some of which may be represented in mammalian genomes. The question remains of how to identify potentially highly divergent mammalian homologs. One possibility is to wait
Transcriptional Regulation by Thyroid Hormone Receptor in Chromatin
Genomic DNA in eukaryotic cells is packaged with histone and nonhistone proteins into chromatin structure. Both biochemical and genetic evidences indicate that chromatin structure imposes constraints on nuclear processes including
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